تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Febrile neutropenia comparison between solid tumors and hematological malignancies
Febrile neutropenia comparison between solid tumors and hematological malignancies
 
لغة الوثيقة : الانجليزية 
المستخلص : Our aim was to study all patients with febrile neutropenia (FN) admitted between April 2000 and December 2003 at King Abdul Aziz University Hospital (KAUH). Data of all patients with FN in solid tumours (ST) and hematological malignancies (HM) were collected and analyzed. A total of 73 admissions of 51 patients admitted with FN (46 admissions with ST and 27 with HM). Seventy four percent were < 50 years of age and 26% > 50 years. Males were 46.6% while females 53.4%. Saudis were 19.2% while non Saudis were 80.8%. Duration of neutropenia was <7days in 43 (58.9%) admissions with ST, 3 (4.1%) admissions with HM while >7days, 3 (4.1%) admissions with ST and 24 (32.9%) with HM (p-value <0.001). Positive cultures were found only in 7 (9.6%) patients with ST vs 18 (24.7%) in HM (p-value <0.001). Positive blood cultures were higher in HM compared to ST (68% vs 16%; p-value 0.053).There was no difference between ST and HM in use of growth factors (p-value 0.606), presence of medical co-morbidity (p-value 0.348) or treatment outcome (p-value 0.137).Twenty one out of 25 positive cultures were found in the blood; 14 with gram-positive bacteria, 5 with gram-negative bacteria, fungal infection in 4 and mixed organisms in 2 cultures. Duration of neutropenia and co-morbidity were the only factors which have leaded to poor outcome. Conclusion: Febrile neutropenia is more common and serious in HM than ST. Culture with gram-positive organisms are higher than gram-negative ones. Pattern of infection varies between hospitals for which each institute should have their own guidelines to manage such cases. 
ردمد : 1012-8832 
اسم الدورية : Pan Arab Medical Journal 
المجلد : 2 
العدد : 4 
سنة النشر : 1426 هـ
2005 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Monday, February 7, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
محمود الاحولAl-Ahwal, Mahmoud باحث رئيسيدكتوراه 
فاتن السايسAl-Sayes, Fatin باحث مشاركدكتوراه 

الملفات

اسم الملفالنوعالوصف
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