تفاصيل الوثيقة نوع الوثيقة : مقال في مجلة دورية  عنوان الوثيقة : NEUTROPENIA IN SYSTEMIC LUPUS ERYTHEMATOSUS NEUTROPENIA IN SYSTEMIC LUPUS ERYTHEMATOSUS   لغة الوثيقة : الانجليزية  المستخلص : Background: systemic lupus erythematosus (SLE) is a multisystem disease of unclear eitiology .Neutropenia occurs in approximately half of SLE patients .Infection is a major cause of morbidity and mortality in those SLE patients . Multiple causes have been involved in the increased susceptibility to infection in such patients. Objectives : This study was conducted to document the frequency of neutropenia and its implication on infection risk among our SLE patients. Methodology: Retrospectively, we studied 61 SLE patients from January 2000 to December 2005. Information collected included age, sex, nationality, absolute neutrophil count and history of infection before treatment. Results: Sixty one patients were found to have SLE, 91.8% were females, while males were 8.2% with a female to male ratio of 11.2:1. The mean age of SLE patients was 26.27 years with a SD + 10.06.Neutropenia was found in 47.4% of patients, 69% of them had moderate to severe type.Infections were documented in 31.1% of SLE patients, 63.1% of them were neutropenic. Urinary tracts followed by chest were the two main sites for infection. Conclusion: In the current study, neutropia is common among our SLE patients. Infection was demonstrated in about one third of the cases, the majority of them were neutropenic. However, neutropenia is one among multiple causes for decreases resistance to infection in untreated active SLE patients.  ردمد : 1319-1004  اسم الدورية : Egypt Rheumatol Rehabilitation  المجلد : 33  العدد : 1  سنة النشر : 1426 هـ 2006 م  نوع المقالة : مقالة علمية  تاريخ الاضافة على الموقع : Sunday, April 18, 2010  الباحثون اسم الباحث (عربي) اسم الباحث (انجليزي) نوع الباحث المرتبة العلمية البريد الالكتروني العنود الجفري AL-JIFRI, AL-ANOUD باحث دكتوراه anoud_jif@hotmail.com فاتن السايس AL-SAYES, FATIN باحث دكتوراه fatinsayes@yahoo.com الملفات اسم الملف النوع الوصف  26544.doc doc   الرجوع إلى صفحة الأبحاث